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A few studies have found that humans prefer sexual partners with only moderately different or even similar MHC variants, others have found that MHC diversity is detected by facial shape rather than smell, and still more have found that women in committed relationships are most attracted to men with different MHC alleles.Some studies have also discovered that women on birth control pills tend to prefer men with the same MHC variants, the opposite of their peers not on the pill.Unlike some direct-to-consumer genetic testing companies (such as those claiming to offer genetically tailored nutritional supplements, which have been subject to enforcement by the Federal Trade Commission for deceptive claims), there is some legitimate science behind the new DNA-matching dating websites.While genetics seems to play some role in human sexual attraction, it clearly is not the only, or even predominant, factor determining human mate choice.In 2008, a company called Gene Partner began to offer genetic testing to identify relationship compatibility.

It has long been known that other mammals, such as mice, selectively mate with partners having different genetic variants of their MHC genes, which control immune responses.Once the “spit, seal & mail” process is complete and the kit is received, Instant Chemistry goes to work to analyze three specific genes in the MHC complex on chromosome six.In assessing compatibility, Instant Chemistry also considers the impact of the serotonin transporter gene to gain insight into one’s emotional response to encountered situations.Over the centuries, physics, chemistry, and biology have transformed what once was seen as mysterious or even magical—the rotation of the stars, flowers blooming, causes of disease—into well-understood phenomena.Could the same now be happening to love and lust, the most mysterious and magical of all human emotions?

Over the next decade, we will have the opportunity to learn about all kinds of predispositions and proclivities buried in our DNA, from health risks to behavioral tendencies to traits affecting abilities such as intelligence, athleticism, and musical talent.

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